You honestly expected anything more elaborate or hedging? What's wrong with you?
Federal laws override state and local laws. That's a basic thing that keeps the country as a single functioning country and not just 50 squabbling state-nation-states. That is called the Supremacy Clause, and it is Article VI, Clause 2 of the US Constitution. Let's read:
"This Constitution, and the Laws of the United States which shall be made in pursuance thereof; and all treaties made, or which shall be made, under the authority of the United States, shall be the supreme law of the land; and the judges in every state shall be bound thereby, anything in the constitution or laws of any state to the contrary notwithstanding."
Attempts at nullification are pretty much a direct assault on the Constitution and as a result never survive a Supreme Court hearing. Nullification got smacked down in 1796, 1816, 1819, 1821, 1859, 1920, 1956, 1982, 1989, 2000, and especially 1958, when the Court straight-up said states have to enforce federal law- in that case, desegregation- even if they disagree with it.
Oh, and don't forget that little war we had in which one side was in favor of nullification and one side wasn't. The pro-nullification side lost.
But I guess we have to go through this again.